News and Announcements
Final Agenda of the Workshop
The Final Agenda and the Abstracts Booklet of the OpenRiskNet is available on the web site.
Materials and tutorials for the Deployment Workshop available to participants
The hands-on workshop will shows how to deploy containerised applications to an OpenRiskNet Virtual Environment. It provides background information and simple examples of deploying applications. Some basic understanding of using containers (e.g. Docker) is assumed.
OpenRiskNet webinars concluded
With ten webinar sessions organised in 2019 and four introduction sessions in 2018, OpenRiskNet outreached ~300 participants from different sectors and related areas like risk assessment, e-infrastructures, nanosafety, modelling, toxicology, AOPs or regulatory.
All materials produced during these sessions (video recordings, slides, additional resources) are available online.
Reserve the dates for the Final OpenRiskNet Workshop: 23-24 October 2019
We are pleased to announce the final OpenRiskNet workshop that will be organised in Amsterdam, The Netherlands on 23-24 October 2019.
The federation of computing and data resources between the OpenRiskNet e-infrastructure and public computational and data resources has now been demonstrated
The OpenRiskNet Consortium develops the OpenRiskNet e-infrastructure for the harmonisation and improved interoperability of data and software tools in the area of predictive toxicology and risk assessment. It aims to combine interoperable web services providing data or analysis, processing and modelling tools communicating over well-defined and harmonised application programming interfaces (APIs), supplemented by a semantic interoperability layer added to every service to describe the functionality whilst guaranteeing the technical and semantic interoperability.
An important task in the project, related also to the TGX case study, involved the federation of compute and data resources between the OpenRiskNet e-infrastructure and external resources. The reference environment has been designed to be capable of handling the majority of requirements for users wishes to deploy and run services. However specific situations demand solutions where either the computation, the data or both reside outside the OpenRiskNet e-infrastructure.
How to identify and link of data related to AOPWiki to support the Adverse Outcome Pathway approach
The Adverse Outcome Pathway (AOP) concept has been introduced to support risk assessment . An AOP comprises a number of biological events: a molecular initiating event (MIE) is followed by one or more key events (KEs), leading to the adverse outcome (AO). The AOPWiki  is a collaborative platform to exchange AOP-related knowledge.
The use of AOPs for regulatory purposes requires detailed validation and linking to existing knowledge [3; 4]. Part of the development of AOPs is the search for data that supports the occurrence and biological plausibility of KEs and their relationships (KERs). This data can be found in literature and increasingly in databases.