News and Announcements
How to identify and link of data related to AOPWiki to support the Adverse Outcome Pathway approach
The Adverse Outcome Pathway (AOP) concept has been introduced to support risk assessment . An AOP comprises a number of biological events: a molecular initiating event (MIE) is followed by one or more key events (KEs), leading to the adverse outcome (AO). The AOPWiki  is a collaborative platform to exchange AOP-related knowledge.
The use of AOPs for regulatory purposes requires detailed validation and linking to existing knowledge [3; 4]. Part of the development of AOPs is the search for data that supports the occurrence and biological plausibility of KEs and their relationships (KERs). This data can be found in literature and increasingly in databases.
Data curation workflows using OpenRiskNet approach ready for demonstration
In the process of utilising the analysis tools available in the OpenRiskNet e-infrastructure, data needs to be accessed from different sources and various formats. Thus, the users should be able to access different data sources and specific entries. This are then being curated using an OpenRiskNet service and re-submitted to the data source.
Within DataCure case study, we aimed to establish a process for data curation and annotation that makes use of APIs and semantic annotations for a more systematic and reproducible data curation workflow. The development of semantic annotations and API definition for selected databases are also desired.
OpenRiskNet and NanoCommons at SOT 2019
The two sister infrastructure projects OpenRiskNet and NanoCommons will present the two complementary approaches to provide users with risk assessment data, software and workflows at the ToxExpo part of the SOT 58th Annual Meeting in Baltimore (10-14 March 2019).
New deliverables reports are publicly available
OpenRiskNet case studies enter final, test phase
OpenRiskNet’s work on case studies is entering the final phase with the focus on demonstrating infrastructure capabilities and on testing different risk assessment scenarios. The case studies provide examples and prototypes for solutions provided to the predictive toxicology and risk assessment community and demonstrate usage of the developed APIs and the interoperability features to build integrated workflows.
OpenRiskNet e-infrastructure listed to EOSC and eInfraCentral catalogues
OpenRiskNet e-infrastructure is listed as a service under the catalogues of European Open Science Cloud (EOSC) and European E-Infrastructure Services Gateway (eInfraCentral).
Additional services, part of OpenRiskNet e-infrastructure, will be also listed.
Update 2019-Feb-26: News posted by eInfraCentral http://einfracentral.eu/news/openrisknet-joined-eosc-catalogue
Ontology meeting by OpenRiskNet and NanoCommons
The goal of this meeting is to get a picture of the ongoing ontology activities in the toxicology area, harmonize these efforts and the developed ontologies therein, and extend the existing toxicology ontology to support OpenRiskNet and NanoCommons tasks. Part of this will be the ontological annotation of OpenRiskNet Application Programming Interfaces (APIs) as used on their cloud.